Faculty/Staff

Laura Jarboe

  • Associate Professor

Main Office

4130 Biorenewables Research Laboratory
Ames, IA 50011
Phone: 515-294-2319




Education

Postdoctoral Researcher, University of Florida, Department of Microbiology and Cell Science/Florida Center for Renewable Fuels and Chemicals, 2006-2008 Ph.D. Chemical & Biomolecular Engineering, University of California, Los Angeles, 2006 B.S. Chemical Engineering with Environmental Engineering Certificate, University of Kentucky, 2000

Interest Areas

  • Substrate or product tolerance in bacteria
  • Fermentation of biomass-derived sugars
  • Reverse engineering evolved bacteria
  • Soil attachment by bacteria
News releases Teaching Fall Semester 2017
  • Ch E 358, Separations (Section A)

Selected Publications

Terms and topics represented in Dr. Jarboe’s 2015 publications.
  • Zaigao Tan, Jong Moon Yoon, David R. Nielsen, Jacqueline V. Shanks, Laura R. Jarboe, "Membrane engineering via trans unsaturated fatty acids production improves Escherichia coli robustness and production of biorenewables," Metabolic Engineering, Vol. 35, May 2016, Pages 105-113 http://www.sciencedirect.com/science/article/pii/S1096717616000252
  • Martha R. Zwonitzer,* Michelle L. Soupir, Laura R. Jarboe, Douglas R. Smith, "Quanifying Attachment and Antibiotic Resistance of Escherichia coli from Conventional and Organic Swine Manure," Journal of Environmental Quality, February 12, 2016 https://dl.sciencesocieties.org/publications/jeq/pdfs/0/0/jeq2015.05.0245
  • Jieni Lian, Jinlyung Choi, Yee Shiean Tan, Adina Howe, Zhiyou Wen, Laura R. Jarboe, "Identification of Soil Microbes Capable of Utilizing Cellobiosan," PLOS ONE (2016) http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149336
  • J. Lian, R. McKenna, M.R. Rover, D.R. Nielsen, Z. Wen, L.R. Jarboe* “Production of Biorenewable Styrene: Utilization of Biomass-Derived Sugars and Insights into Toxicity”, Journal of Industrial Microbiology and Biotechnology (2016) http://link.springer.com/article/10.1007/s10295-016-1734-x?wt_mc=internal.event.1.SEM.ArticleAuthorOnlineFirst
  • Y. Shen, L. Jarboe, R.C. Brown, Z. Wen* “A thermochemical-biological hybrid processing of lignocellulosic biomass for producing fuels and chemicals” Biotechnology Advances 33(8):1799-813 (2015) http://www.sciencedirect.com/science/article/pii/S0734975015300446
  • J.P. Bacik*, J.R. Klesmith, T.A. Whitehead, L.R. Jarboe, C.J. Unkefer, B.L. Mark, R. Michalczyk “Producing glucose-6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion” Journal of Biological Chemistry 290:26638-26648 (2015) http://www.jbc.org/content/early/2015/09/09/jbc.M115.674614
  • C. Liao, X. Liang, M. Soupir*, L. Jarboe “Cellular, particle and environmental parameters influencing attachment in surface waters: a review” Journal of Applied Microbiology 119(2):315-330 (2015) http://onlinelibrary.wiley.com/doi/10.1111/jam.12860/full
  • J. Trcek*, N.P. Mira, L. Jarboe* “Adaptation and tolerance of Bacteria against Acetic Acid” Applied Microbiology and Biotechnology 99(15):6215-29 (2015) http://link.springer.com/article/10.1007%2Fs00253-015-6762-3
  • L.A. Royce, J.M. Yoon, Y. Chen, E. Rickenbach, J.V. Shanks, L. Jarboe*, “Evolution for exogenous octanoic acid tolerance improves carboxylic acid production and membrane integrity” Metabolic Engineering 29:180-188 (2015) http://www.sciencedirect.com/science/article/pii/S1096717615000403
  • Y. Fu, J.M. Yoon, L. Jarboe, J. Shanks*, “Metabolic Flux Analysis of Escherichia coli MG1655 under Octanoic Acid (C8) Stress” Applied Microbiology and Biotechnology 99:4397-408 (2015) http://link.springer.com/article/10.1007/s00253-015-6387-6/fulltext.html
  • X. Liang, M. Soupir*, S. Rigby, L. Jarboe, W. Zhang. “Flow cytometry is a promising and rapid method for differentiating between freely suspended E. coli and E. coli attached to clay particles” Journal of Applied Microbiology, 2014, 117:1730-1739 http://onlinelibrary.wiley.com/doi/10.1111/jam.12660/abstract
  • T.J. Claypool, D.R. Raman*, L.R. Jarboe, D.R Nielsen. “Technoeconomic evaluation of Bio-Based Styrene production by Engineered Escherichia coli” Journal of Industrial Microbiology and Biotechnology, 2014, 41(8):1211-6 DOI 10.1007/s10295-014-1469-5 http://link.springer.com/article/10.1007%2Fs10295-014-1469-5
  • L.A. Royce, E. Boggess, Y. Fu, P. Liu, J.V. Shanks, J. Dickerson, L. Jarboe* “Transcriptomic analysis of carboxylic acid challenge in Escherichia coli: beyond membrane damage” PLOS ONE 2014, 9(2):e89580 DOI:10.1371/journal.pone.0089580 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0089580
  • L. A. Royce, P. Liu, M. J. Stebbins, B. C. Hanson, L. R. Jarboe.* “The damaging effects of short-chain fatty acids on Escherichia coli membranes” Applied Microbiology and Biotechnology 2013 97:8317 DOI 10.1007/s00253-013-5113-5 http://link.springer.com/article/10.1007%2Fs00253-013-5113-5
  • L. A. Royce, E. Boggess, T. Jin, J. Dickerson, L. Jarboe.* “Identification of Mutations in Evolved Bacterial Genomes” Methods in Molecular Biology (vol 985): Systems Metabolic Engineering: Methods and Protocols, Hal Alper (ed). 2013 http://dx.doi.org/10.1007/978-1-62703-299-5
  • P. Liu, A. Chernyshov, T. Najdi, Y. Fu, J. Dickerson, S. Sandmeyer, L. Jarboe.* “Membrane stress caused by octanoic acid in Saccharomyces cerevisiae.” Applied Microbiology and Biotechnology 2013 97(7):3239 – 3251. 10.1007/s00253-013-4773-5. http://link.springer.com/article/10.1007%2Fs00253-013-4773-5
  • K. B. Kautharapu, J. Rathmacher, L. Jarboe.* “Growth condition optimization for docosahexaenoic acid (DHA) production by Moritella marina MP-1.” Applied Microbiology and Biotechnology 2013 97(7):2859 – 2866. DOI: 10.1007/s00253-012-4529-7 http://www.springerlink.com/content/n37573r377502523/
  • L. Jarboe,* P. Liu, K. Kautharapu, L. O. Ingram. “Optimization of enzyme parameters for fermentative production of biorenewable fuels and chemicals.” Computational and Structural Biotechnology Journal. October 2012. 3(4) e201210005, http://dx.doi.org/10.5936/csbj.201210005
  • P. Liu, L. Jarboe.* “Metabolic Engineering of biocatalysts for carboxylic acids production” Computational and Structural Biology 2012. 3(4) e201210011, http://dx.doi.org/10.5936/csbj.201210011
  • L. R. Jarboe*, Ping Liu, Liam Royce. “Engineering inhibitor tolerance for the production of biorenewable fuels and chemicals”. Current Opinion in Chemical Engineering. 2011 (invited) 1:38-42. http://dx.doi.org/10.1016/j.coche.2011.08.003
  • Liu, P., M. L. Soupir, M. Zwonitzer, B. Huss, L. Jarboe.* “Antibiotic Resistance in Agricultural E. coli Isolates is Associated with Attachment to Quartz” AEM. 2011. 77(19):6945-6953. http://dx.doi.org/10.1128/AEM.00717-11
  • L. R. Jarboe*, Z. Wen, D. W. Choi, R. C. Brown. “Hybrid thermochemical processing: fermentation of pyrolysis-derived bio-oil”. Applied Microbiology and Biotechnology. 2011 (invited) 91(6):1519-1523. http://dx.doi.org/10.1007/s00253-011-3495-9
  • D. Layton, A. Ajjarapu, D.W. Choi, L. Jarboe.* Engineering ethanologenic Escherichia coli for levoglucosan utilization, Bioresource Technology. 2011 102:8318-8322. http://dx.doi.org/10.1016/j.biortech.2011.06.011
  • Jarboe, L. R.* 2010. YqhD: A broad-substrate range aldehyde reductase with various applications in production of biorenewable fuels and chemicals, Applied Microbiology and Biotechnology. http://dx.doi.org/10.1007/s00253-010-2912-9
  • Turner, P. C., E. N. Miller, L. Jarboe , C. L. Baggett, K. T. Shanmugam, L. O. Ingram*  2010.  YqhC regulates transcription of the adjacent Escherichia coli genes yqhD and dkgA that are involved in furfural tolerance. J Industr Microbiol Biotechnol. DOI 10.1007/s10295-010-0787 -5. http://www.springerlink.com/content/d003u8203g763005/
  • Miller, E. N., P. C. Turner, L. R. Jarboe , L. O. Ingram.* 2010. Genetic changes that increase 5-hydroxymethyl furfural resistance in ethanol-producing Escherichia coli LY180. Biotechnology Letters. 32(5):661-667. http://www.springerlink.com/content/l147081327744512/
  • L. R. Jarboe , X. Zhang, X. Wang, J.C. Moore, K.T. Shanmugam, L.O. Ingram* 2010. Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology (invited) Journal of Biomedicine and Biotechnology. Article ID 761042 Cited: 1 http://www.hindawi.com/journals/jbb/2010/761042.html
  • Miller, E. N., L. R. Jarboe , P. C. Turner, P. Pharkya, L. P. Yomano, S. W. York, K. T. Shanmugam, L. O. Ingram*. 2009. Furfural Inhibits Growth by Limiting Sulfur Assimilation in Ethanologenic Escherichia coli strain LY180. Applied and Environmental Microbiogy. 75(19):6132-6141. http://aem.asm.org/cgi/content/full/75/19/6132
  • Miller, E. N., L. R. Jarboe , L. P. Yomano, S. W. York, K. T. Shanmugam, L. O. Ingram*. 2009.  Silencing of NADPH-dependent Oxidoreductases (yqhD and dkgA) in Furfural-Resistant Ethanologenic Escherichia coli . Applied and Environmental Microbiology 75(13):4315-4323. http://aem.asm.org/cgi/content/full/75/13/4315
  • Jarboe, L. R. 1 , D. R. Hyduke 1 , L. M. Tran, K. J. Y. Chou and J. C. Liao*. 2008. Determination of the Escherichia coli S-nitrosoglutathione response network using integrated biochemical and systems analysis. Journal of Biological Chemistry 283(8):5148-5157. 1 co-first authors. http://www.jbc.org/cgi/content/full/280/11/10065
  • Jarboe, L. R., T. B. Grabar, L. P. Yomano, K. T. Shanmugam, L. O. Ingram*. 2007. Development of Ethanologenic Bacteria Advances in Biochemical Engineering: Biofuels. Ed. L. Olsson. Springer. http://www.springerlink.com/content/w34780x4t1gxrp55/
  • Hyduke, D. R. 1, L. R. Jarboe 1, L. M. Tran, K. C. Chou and J. C. Liao*. 2007. Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli. PNAS 104(20):8484-8489. 1 co-first authors. http://www.pnas.org/content/104/20/8484
  • Jarboe, L. R., D. Beckwith and J. C. Liao*. 2004. Stochastic Modeling of the Phase-Variable pap Operon Regulation in Uropathogenic Escherichia coli. Biotechnology and Bioengineering 88(2):189-203. http://www3.interscience.wiley.com/cgi-bin/fulltext/109658796/PDFSTART
  • Jarboe L. R., D. R. Hyduke, J. C. Liao*.  2009.  Systems Approaches to Unraveling Nitric Oxide Response Networks in Prokaryotes. Nitric Oxide (2nd Ed) Ed. L. Ignarro. Elsevier.
  • Luli, G.W., L. R. Jarboe , L. O. Ingram. 2008. The development of ethanologenic bacteria for fuel ethanol production. Bioenergy. 129-137.
  • Jarboe, L. R., K. T. Shanmugam, L. O. Ingram. 2007. Ethanol Encyclopedia of Microbiology (3rd Ed) Ed. D. Majumder-Russell. Elsevier.